Peptide Therapy

MOTS-c

Mitochondrial-derived exercise mimetic

From $260/mo

Pricing varies by protocol

MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome. It activates AMPK — the body’s master metabolic switch — through a unique mechanism involving one-carbon metabolism. Research suggests it replicates several molecular signatures of endurance exercise, earning it the label of ‘exercise mimetic.’

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Licensed Providers · Lab-Guided · Ongoing Support

Key Benefits

AMPK Activation — Activates the master metabolic regulator through a distinctive pathway involving folate cycle modulation and endogenous AICAR accumulation.
Metabolic Support — Research demonstrates increased glucose utilization, enhanced fatty acid oxidation, and improved insulin sensitivity.
Exercise Enhancement — Circulating MOTS-c levels increase with exercise; exogenous administration may complement training benefits.
Longevity Research — Mitochondrial-derived peptide studied in aging models for its potential to support cellular metabolism and healthspan.

How It Works

Your provider reviews your labs and health history, then prescribes a personalized protocol. Medication is shipped directly to your door from a licensed 503A pharmacy. Your provider monitors your progress with regular lab work and adjusts your plan as needed.

What to Expect

Many patients report improved energy, exercise tolerance, and metabolic markers within 4–6 weeks. Your provider will tailor dosing to your metabolic profile and fitness goals.

MOTS-c

Who It's For

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